Cochrane Database Syst Rev . The basic side effects of evening primrose are rare and include the mild cases of stomach pain, headaches, nausea, and diarrhea. You should talk with your health care provider for complete information about the risks and benefits of using this product. This medication contains evening primrose oil. This is only a brief summary of general information about this product. Phospholipids contained in EPO help to dissolve the existing subcutaneous fat. It can help clear up acne. The dosage of EPO for breast pain is the following: take 3,000 mg daily for 6 months. They include nausea, headache, stomach, pain and loose stools. Several studies have shown, that supplements with gamma-linolenic acid can reduce both inflammatory and non-inflammatory acne lesions. This website is supported by different affiliates and we receive a paid commission on certain products from our advertisers. Although proponents claim that this oil may help with conditions such as eczema, dry eye, chronic pain, and women’s hormonal issues, there is insufficient evidence to support most uses. Possible side effects of evening primrose oil for weight loss Negative effects from taking evening primrose oil for weight loss are mild digestive issues and headaches. Evening primrose oil has been administered orally in clinical trials at doses between 6 and 8 g/day in adults and 2 and 4 g/day in children. Taking EPO may help to relieve breast pain. Information regarding safety and efficacy in pregnancy and lactation is lacking. The rare side effects that do occur usually are mild and may mean the dose is too high. However, this relationship was not proven in a pharmacokinetic study in healthy participants.5, Atopic eczema/dermatitis syndrome has been recommended by an international task force to encompass all forms of eczema, including atopic dermatitis.67 A number of reviews and randomized clinical trials show a lack of support for the use of evening primrose oil for atopic dermatitis.6, 7, 8, 9 Many of the trials are of poor quality and have apparent issues of bias.9, 10, 11 In 2013, a Cochrane review evaluated 19 placebo-controlled, randomized clinical trials conducted in adults and children that assessed evening primrose oil for the treatment of signs and symptoms of eczema. Evening primrose oil is a source of GLA. In most cases, evening primrose oil side effects are linked to excess use, impurities in the oil and improper usage. The dose is calculated on the basis of a clinical study [1]. With the exception of certain products that are generally recognized as safe in normal quantities, including use of folic acid and prenatal vitamins during pregnancy, this product has not been sufficiently studied to determine whether it is safe to use during pregnancy or nursing or by persons younger than 2 years of age. Shine Evening Primrose Oil Vitamin E(Evening primrose oil 1,000 mg, vit E 13 IU): Health supplement. Mucilage and tannin in the plant parts have been analyzed.2, Essential fatty acids are important as cellular structural elements and as precursors of prostaglandins. Evening primrose oil for eczema: no more itch? Suitable dosage of evening primrose oil depends on many factors. When compared to changes seen with placebo, supplementation with vitamin D and evening primrose oil for 6 weeks produced significant improvements in vitamin D levels (−0.1 vs +6.9 ng/mL, P<0.001); fasting plasma glucose (−3.6 vs +1.5 mg/dL, P=0.04); serum insulin concentrations (−2 vs +4.6 microunits/mL, P=0.004); homeostasis model of assessment-insulin resistance (HOMA-IR; −0.5 vs +1.1, P=0.003); HOMA-beta-cell function (−7.7 vs +17.4, P=0.007); triacylglycerol (−20 vs +34.3 mg/dL, P<0.001); very low-density lipoprotein (−4 vs +6.9 mg/dL, P<0.001), low-density lipoprotein (−18 vs +1.8 mg/dL, P=0.001), and total cholesterol (−22.1 vs +5.3 mg/dL, P<0.001); as well as the ratio of total to high-density lipoprotein (HDL) cholesterol (−0.3 vs +0.3 mg/dL, P<0.001). Too high of an evening primrose oil dosage can result in stomach pain, headache and diarrhea. Evening primrose oil can help with conditions such as arthritis for older dogs, as well as the pain and discomfort of dry, itchy skin. Minimize Breast Pain. Starting around 37 weeks insert 1 capsule (500 mg) vaginally every evening before going to bed. When Buying: Look for high-quality evening primrose oil certified as organic by a reputable third party. We comply with the HONcode standard for trustworthy health information -. In combination with vitamin D, evening primrose oil has improved glycemic and lipid profiles in women with gestational diabetes. Evening primrose oil is likely safe when taken by mouth in suggested doses for up to one year for premenstrual syndrome (PMS), breast pain, or eczema (atopic dermatitis). These two acids are thought to be the healing ingredients in EPO. Evening primrose oil dosage: The dosage usually depends on what you are taking it for and varies widely depending on where you are doing your research. What Are The Best Essential Oils For Nail Fungus? – Evening primrose only is only considered safe if taken in the right dosage. ... What is evening primrose oil? Most of these side effects can be avoided by starting the treatment in … Evening Primrose Oil Side Effects and Dosage. Evening Primrose Oil Dosage may vary from 500 mg to 3000mg depending on the health condition. READ >>> What you need to know before taking Evening primrose oil to induce labor naturally. Due to the lack of research, evening primrose should be not be used in children. A typical dosage of evening primrose oil, standardized to contain eight percent GLA, is two to eight grams per day. The benefits of evening primrose oil include its ability to soothe inflammation, strengthen the bones, promote good skin health, balance hormones, lower cholesterol, optimize digestion, regulate blood sugar levels, prevent hair loss, ease pain and aid in weight loss efforts.. Learn its uses and side-effects when treating rheumatoid arthritis. Originating from North America, evening primrose is a flowering, yellow plant traditionally used to heal bruises and treat a variety of skin conditions. Therefore, always pay attention to the information on the label regarding the oil content. This oil contains a fatty acid called gamma-linolenic acid, or GLA for short, as well as linoleic acid. Evening primrose oil is available in many health food stores or pharmacies and is typically sold in gel cap form. There are no further reports of seizures related to evening primrose oil, which may actually have a protective effect.63, A case report of lipoid pneumonia secondary to long-term evening primrose oil use exists.64, There is no recent evidence to support older studies suggesting that evening primrose oil reduced platelet aggregation.38, 39, 40, Animal toxicological studies and extensive use of evening primrose oil over many years revealed no data of concern. It is commonly used for eczema and skin disorders in both human beings and animals. If you are among those people, always consider the size of the evening primrose oil capsule. This information is not specific medical advice and does not replace information you receive from your health care provider. It may take up to six months until you see noticeable results. Select one or more newsletters to continue. The liquid doses are usually much smaller but it can vary from product to product. The recommended dose is 500mg of evening primrose oil capsule daily or 360 mg to 480 mg GLA from evening primrose oil daily for six months. This oil is also good for other inflammatory conditions of the skin, such as psoriasis and eczema, and can protect wounds and cuts from infection. Evening Primrose Oil. Most health stores sell dietary supplements containing evening primrose oil (EPO), which is extracted from the plant's seeds. Evening primrose oil may be safe for use during pregnancy and while breastfeeding, but the evidence is not conclusive. Taking up to 4 grams daily for … No toxicity, carcinogenicity, or teratogenicity has been reported. Always seek the advice of a physician or other qualified health provider with any questions you may have regarding a medical condition. Bottled primrose oil is also available but is m… A case report exists of transient petechiae in a newborn following oral and intravaginal use of evening primrose oil for cervical ripening for a week prior to the infant's birth. Trending A range of evening primrose oil products are available for purchase online. Topical application of evening primrose oil is used to relieve pain, but its efficacy for nerve pain has not been ascertained. This dose is equivalent to five 500mg capsules (2500mg of evening primrose oil). Originating from North America, evening primrose is a flowering, yellow plant traditionally used to heal bruises and treat a variety of skin conditions. GLA helps support women during the premenstrual period. Used as recommended, EPO is generally considered safe. Evening Primrose Oil Side Effects and Dosage. Both linoleic and GLA are normally present in breast milk, and it is reasonable to assume that evening primrose oil may be taken while breast-feeding. It is used for its natural healing properties. Recommended dosage Evening primrose oil can be obtained in health food stores in either liquid or capsule form. The most common side effects are temporary gastrointestinal symptoms such as abdominal pain, fullness, or nausea. This product may adversely interact with certain health and medical conditions, other prescription and over-the-counter drugs, foods, or other dietary supplements. Disease Dosage Frequency; acne. We use cookies to ensure that we give you the best experience on our website. Evening primrose oil acne dosage equals to 1000mg daily. However, it will be the doctor or nutrition specialist who recommends the most appropriate dose. In fact, it is widely advertised nowadays by many bloggers, and you won’t find a gynecologist who won’t speak of oil … Evening primrose oil is the oil derived from the seeds of the evening primrose (Oenothera biennis) plant.It has a number of popular uses and is widely available in supplement form. 1. Hot Evening primrose is LIKELY SAFE for most people when used in doses up to 6 grams daily for up to a year. Consider therapy modification.59, 60, 61, 62, Two clinical studies conducted in the 1980s among individuals with schizophrenia led to a concern that evening primrose oil might lower the seizure threshold. If you have trouble swallowing even the smallest pills, you might consider taking liquid evening primrose oil. Vitamin E is a fat-soluble antioxidant known for its ability to build and repair tissues . The typical content of gamma-linolenic acid (GLA) in the oil is 8% to 10%. Evening primrose is LIKELY SAFE for most people when used in doses up to 6 grams daily for up to a year. Bleeding may occur. EPO capsules (500–1,300 mg) or oil (150 ml) are available from high-street retailers. Warnings. Meta-analyses conducted with 7 studies using participant-reported improvements (n = 176) and 8 using physician-assessed improvements (n = 289) support previous reports of the lack of effectiveness of evening primrose oil.67, While an older review suggested promising results12 the most comprehensive meta-analysis to date did not establish efficacy.10 Clinical studies continue to be conducted, with a gradual time-dependent improvement suggested.13, There is no recent evidence to support older studies38, 39, 40 suggesting that evening primrose oil reduced platelet aggregation. Usually, mild side effects like headache, nausea, upset stomach and loose stools, are experienced by some of the users. A trend toward reduction of morning stiffness and joint tenderness, as well as pain relief, has been shown. Evening primrose oil was previously suspected to lower the seizure threshold in schizophrenic patients; however, this is now disputed. Bleeding may occur. Popular. As a nutritional supplement, the maximum label-recommended daily dose of evening primrose oil is approximately 4 g, containing 300 to 360 mg of GLA.2. The recommended evening primrose oil dosage is 1-6 capsules a day, at a dose of 500 milligrams per capsule. Is evening primrose oil acne clearing? EPO is rich in polyunsaturated omega-6 fatty acids that can help control pain and inflammation. It is used for its natural healing properties. Often people ask themselves – how much evening primrose oil should I take? Evening primrose oil (EPO) is among the best treatments that can be used to relieve menopause symptoms. There is no official upper limit for EPO, but the European Medicines Agency warns that children under 12 should not take it.17 You should also avoid taking EPO if you:18 1. are on blood thinning drugs like warfarin, as EPO has blood-thinning effects 2. are due to have surgery in two weeks 3. have epilepsy, s… The fruit is a dry pod approximately 5 cm long that contains many small seeds.1, 2, 3, Seeds from O. biennis contain 14% of a fixed oil known as evening primrose oil that can contain 50% to 70% cis-linoleic acid and 7% to 10% cis-GLA. Skin Health: Evening Primrose Oil contains GLA to help maintain the appearance of healthy skin and can help assist with dryness and itching associated with mild skin conditions. Contents of evening primrose oil per capsule may be different for different brands. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to this product. Available for Android and iOS devices. Evening Primrose Oil Side Effects. Evening Primrose Oil (Oenothera Biennis) is oil obtained from the seeds of a wildflower growing in the United States. The normal dose for evening primrose oil is 1000mg to 3000mg/day. Therefore, although the dose depends on the patient and the ailment to be treated, the most common is an intake of 3 capsules of evening primrose oil a day. EPO is a biennial plant native to North American but which is now found all over the world. Evening primrose oil is generally safe when used in recommended dosages, which is 2 to 8 grams daily. This product has not been reviewed by the FDA to determine whether it is safe or effective and is not subject to the quality standards and safety information collection standards that are applicable to most prescription drugs. Any and all trademarks, logos brand names and service marks displayed on this website are the registered or unregistered Trademarks of their respective owners. Additionally, 3 Hot Flash Related Daily Interference Scale subscores improved significantly: social activity, relations with others, and sexuality. Evening primrose is not considered to be safe if used in pregnancy. Evening Primrose Oil (EPO) is becoming very popular for the treatment of menopause symptoms such as mood swings, headaches, anxiety, fluid retention, irritability, and breast tenderness. Capsules and tablets typically contain 500 mg evening primrose oil [ 31 ]. What works for you may not be the best for another. Some people have problems swallowing large tablets or capsules. 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